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by John Papaconstantinou (Author)
Pathways to the Development of the Aging Phenotype explores the journey that all living things must eventually take. Using the definition that aging is a "multifactorial syndrome caused by multiple pathophysiological processes that occur simultaneously in multiple tissues of the aged," Dr. John Papaconstantinou provides a wholistic look at aging, its causes, how it presents, and how aging syndromes can be treated. In addition, this book offers a deeper look at the effects of aging on individual organs. The aging heart, skeletal muscle, eye, skin, kidney, intestine, liver, pancreas, and adipose tissue are all covered, as well as an examination of the aging brain and neurodegenerative diseases such as Alzheimer's, ALS, Parkinson's, and Huntington's disease. Other important subjects covered are the effects of social isolation and loneliness on aging, as well as the effects of sleep and other lifestyle choices.
Throughout the book, Dr. Papaconstantinou provides information on current and promising research on aging and the treatment of aging syndromes, as well as the recent, exciting work on tissue regeneration that suggests aged tissues and organs can be reprogrammed to a juvenile phenotype. Pathways to the Development of the Aging Phenotype is an exciting addition to scientific and medical literature related to aging and will be an invaluable resource for medical students, professionals, and researchers looking to expand their knowledge in this field.
